eating too much fish increases the risk of melanoma

Can eating fish affect your risk of skin cancer? Yes, according to researchers at Brown University in the United States. According to their latest study published on June 9 in the journal Cancer Causes & Control, regular consumption of fish increased the risk of melanoma. The study shows that there is a link between fish consumption and the development of skin cancer. Eating large amounts of fish, especially tuna and unfried fish, is associated with a higher risk of malignant melanoma. Brown University researchers found that the risk of malignant melanoma was 22% higher in people whose median daily fish consumption was 42.8 grams, compared to those whose daily consumption was 3. 2 grams.

Fish: how much puts you at risk?

They also observed that people whose median daily fish consumption was 42.8 grams had a 28% increased risk of developing abnormal cells in the outer layer of the skin only (stage 0 melanoma or melanoma in situ) compared to people whose median daily consumption was 3.2 grams of fish. Note that a portion of fish corresponds to approximately 140 grams of cooked fish. In practice, to examine the relationship between fish consumption and melanoma risk, the authors analyzed data collected from 491,367 adults recruited across the United States as part of the NIH-AARP Diet and Health Study. Study between 1995 and 1996.

The participants, aged 62 on average, reported how often they had eaten fried fish, unfried fish and tuna in the past year, as well as their portion sizes. The researchers therefore calculated the incidence of new melanomas that developed over a median period of 15 years using data obtained from cancer registries. They took into account socio-demographic factors, as well as participants’ BMI, level of physical activity, smoking history, daily alcohol, caffeine and calorie intake, family history of cancer and blood levels. means of UV radiation in their area. As a result, 5,034 participants (1.0%) developed malignant melanoma during the study period and 3,284 (0.7%) stage 0 melanoma.

Skin cancer: 20% higher risk of malignant melanoma

Researchers found that higher consumption of unfried fish and tuna was associated with an increased risk of malignant melanoma and stage 0 melanoma. People with a median daily tuna consumption of 14.2 grams had a 20% higher risk of malignant melanoma and 17% higher risk of stage 0 melanoma, compared to those whose median daily tuna consumption was 0.3 grams. A median consumption of 17.8 grams of unfried fish per day was associated with an 18% increased risk of malignant melanoma and 25% increased risk of stage 0 melanoma, compared to a median consumption of 0.3 grams of unfried fish per day. The researchers did not identify a significant association between fried fish consumption and the risk of malignant melanoma or stage 0 melanoma.

Eunyoung Cho, lead author of the study, speculates that biocontaminants in fish may be linked to this increased risk of skin cancer. “We speculate that our findings could possibly be attributed to contaminants in fish, such as polychlorinated biphenyls, dioxins, arsenic and mercury. Previous research has shown that high fish consumption is associated with increased levels higher levels of these contaminants in the body and identified associations between these contaminants and a higher risk of skin cancer.However, we note that our study did not examine the levels of these contaminants in the participants’ bodies and that further research is therefore needed to confirm this relationship.

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